常杰 苏州医学院公共卫生学院副教授

常杰，女，博士， 苏州医学院公共卫生学院国家一流专业建设秘书、副教授，硕导。

学习经历:

2004.09—2008.06  福建农林大学  学士

2009.04—2011.03  日本三重大学 硕士

2011.04—2014.09  日本名古屋大学 博士

2014.10—2017.06  苏州大学公共卫生学院讲师

2017.07—至今    苏州大学医学部公共卫生学院副教授

学术任职：

1、中国毒理学会神经毒理专业委员会青年委员（2024.09-2028.09）。

2、江苏省毒理学会工业毒理专业委员会委员（2020.12-2024.12）。

3、江苏省环境诱变剂学会环境应激委员会委员（2024.01-2028.01）。

4、苏州市预防医学会职业卫生专业委员会副主任委员（2024.06-2029.06）。

主讲课程：

1.承担本科生教学课程：职业卫生与职业医学，预防医学，健康与社会，医学科研方法，生活方式与健康。

2.承担研究生教学课程：劳动卫生学。 

研究方向：

1.环境污染物与神经损伤；

2.慢性病的健康损伤效应机制及营养干预。

科研项目：

1.苏州大学苏州医学院，10-HDA调控PPARα通路改善糖尿病认知功能障碍的机制研究，2023.10-2025.09，20万元，主持。

2.苏州市科技厅（医疗卫生科技创新），SKY2022114，10-HDA改善糖尿病认知功能障碍的机制及应用研究 ，2022.7- 2025.6，5万元，主持。

3.国家自然科学基金委员会, 青年科学基金项目, 81602840, 白杨素调控自噬影响脂肪细胞增殖分化及脂质代谢的作用与机制研究, 2017.01 – 2019.12, 18万元，主持。

4.国家自然科学基金委员会, 面上项目, 81773414, 高剂量维生素D拮抗镉负荷下糖尿病肾损伤的实验研究, 2018.01 至 2021.12, 65万元, 参与。

5.国家自然科学基金委员会, 面上项目, 81773509, 鞘磷脂与糖尿病及其心血管并发症发病关系的研究, 2018.01至 2021.12, 60万元，参与。

6.国家自然科学基金委员会, 面上项目, 81673126, 氡致肺癌发生中p53介导的线粒体复合损伤机制, 2017.01 至 2020.12, 50万元，参与。

英文论文（*通讯作者）：

1. Huang, Xinqi; Xiu, Lu; An, Yumei; Gong, Yuan; Li, Sunao; Chen, Xueshi; Liu, Chao; Lu, Jianghuiwen; Shan, Haiyan*; Chang, Jie*; Zhang, Mingyang*. Preventive effect of royal jelly and 10-HDA on skin damage in diabetic mice through regulating keratinocyte Wnt/β-catenin and pyroptosis pathway[J]. Molecular Nutrition & Food Research, 2024, 68(19): e2400098.

2.Ge R, You S, Zheng D, Zhang Z, Cao Y, Chang J*. Global, regional, and national temporal trends of diet-related ischemic stroke mortality and disability from 1990 to 2019.Int J Stroke. 2024 Jul;19(6):665-675.

3.Ge R, Wang Y, Zhang Z, Sun H, Chang J*.Association of long-term exposure to various ambient air pollutants, lifestyle, and genetic predisposition with incident cognitive impairment and dementia..BMC Public Health. 2024 Jan 15;24(1):179.

4.  Ge, Rongguang; Chang, Jie*. Disease burden of migraine and tension-type headache in non-high-income East and Southeast Asia from 1990 to 2019[J]. Journal of Headache and Pain, 2023, 24(1): 32.

5.  Ge, Rongguang; Chang, Jie; Cao, Yongjun*. Headache disorders and relevant sex and socioeconomic patterns in adolescents and young adults across 204 countries and territories: an updated global analysis[J]. Journal of Headache and Pain, 2023, 24(1): 110.

6.  Kitamura, Yuki; Oikawa, Shinji; Chang, Jie; Mori, Yurie; Ichihara, Gaku; Ichihara, Sahoko*. Carbonylated proteins as key regulators in the progression of metabolic syndrome[J]. Antioxidants, 2023, 12(4): 844.

7.  Gong, Yuan; Luo, Hongjie; Li, Zeju; Feng, Yijun; Liu, Zhen; Chang, Jie*. Metabolic profile of Alzheimer's disease: Is 10-hydroxy-2-decenoic acid a pertinent metabolic adjuster?[J]. Metabolites, 2023, 13(8): 954.

8.  Hu, Zhi-Yong; Chang, Jie; Guo, Fei-Fei; Deng, Han-Yi; Pan, Guo-Tao; Li, Bing-Yan; Zhang, Zeng-Li*. The effects of dimethylformamide exposure on liver and kidney function in the elderly population: A cross-sectional study[J]. Medicine, 2020, 99(27): 20749.

9.  Rui, Yehua; Lv, Menglian; Chang, Jie; Xu, Jiaying; Qin, Liqiang; Wan, Zhongxiao*. Chia seed does not improve cognitive impairment in SAMP8 mice fed with high fat diet[J]. Nutrients, 2018, 10(8): 1084.

10.  Ichihara, Sahoko*; Suzuki, Yuka; Chang, Jie; Kuzuya, Kentaro; Inoue, Chisa; Kitamura, Yuki; Oikawa, Shinji. Involvement of oxidative modification of proteins related to ATP synthesis in the left ventricles of hamsters with cardiomyopathy[J]. Scientific Reports, 2017, 7(1): 9243.

11.  Rui Yehua; Cheng Jinbo; Qin Liqiang; Shan Cheng; Chang Jie; Wang Guiping; Wan Zhongxiao. Effects of vitamin D and resveratrol on metabolic associated markers in liver and adipose tissue from SAMP8 mice[J]. Experimental Gerontology, 2017, 93: 16-28.

12. Zong, Cai; Zhang, Xiao; Huang, Chinyen; Chang, Jie; Garner, C. Edwin; Sakurai, Toshihiro; Kato, Masashi; Ichihara, Sahoko; Ichihara, Gaku*. Role of cytochrome P450s in the male reproductive toxicity of 1-bromopropane[J]. Toxicology Research, 2016, 5(6): 1522-1529.

13. Zong, Cai; Garner, C. Edwin; Huang, Chinyen; Zhang, Xiao; Zhang, Lingyi; Chang, Jie; Toyokuni, Shinya; Ito, Hidenori; Kato, Masashi; Sakurai, Toshihiro; Ichihara, Sahoko; Ichihara, Gaku*. Preliminary characterization of a murine model for 1-bromopropane neurotoxicity: Role of cytochrome P450[J]. Toxicology Letters, 2016, 258: 249-258.

14. Tada-Oikawa, Saeko; Ichihara, Gaku; Fukatsu, Hitomi; Shimanuki, Yuka; Tanaka, Natsuki; Watanabe, Eri; Suzuki, Yuka; Murakami, Masahiko; Izuoka, Kiyora; Chang, Jie; Wu, Wenting; Yamada, Yoshiji; Ichihara, Sahoko*. Titanium dioxide particle type and concentration influence the inflammatory response in Caco-2 cells[J]. International Journal of Molecular Sciences, 2016, 17(4): 576.

15. Chang, Jie; Ichihara, Gaku; Shimada, Yasuhito; Tada-Oikawa, Saeko; Kuroyanagi, Junya; Zhang, Beibei; Suzuki, Yuka; Sehsah, Radwa; Kato, Masashi; Tanaka, Toshio; Ichihara, Sahoko. Copper oxide nanoparticles reduce vasculogenesis in transgenic zebrafish through down-regulation of vascular endothelial growth factor expression and induction of apoptosis[J]. J Nanosci Nanotechnol, 2015, 15(3): 2140-2147.

16. Zhenlie Huang; Sahoko Ichihara; Shinji Oikawa; Jie Chang; Lingyi Zhang; Shijie Hu; Hanlin Huang*; Gaku Ichihara*. Hippocampal phosphoproteomics of F344 rats exposed to 1-bromopropane[J]. Toxicology and Applied Pharmacology, 2015, 282(2): 151-160.

15. Ichiro Yajima; Machiko Iida; Mayuko Y. Kumasaka; Yasuhiro Omata; Nobutaka Ohgami; Jie Chang; Sahoko Ichihara; Masaru Hori; Masashi Kato*. Non-equilibrium atmospheric pressure plasmas modulate cell cycle-related gene expressions in melanocytic tumors of RET-transgenic mice[J]. Exp Dermatol, 2014, 6: 424-425.

16. Wenting Wu; Gaku Ichihara; Naozumi Hashimoto; Yoshinori Hasegawa; Yasuhiko Hayashi; Saeko Tada-Oikawa; Yuka Suzuki; Jie Chang; Masashi Kato; Corina N. D'Alessandro-Gabazza; Esteban C. Gabazza; Sahoko Ichihara*. Synergistic effect of bolus exposure to zinc oxide nanoparticles on bleomycin-induced secretion of pro-fibrotic cytokines without lasting fibrotic changes in murine lungs[J]. International Journal of Molecular Sciences, 2014, 16(1): 660-676.

中文论文:

1.  常杰, 张增利. “职业卫生与职业医学”课程思政教育的思考与实践[J]. 大学, 2023(24): 133-136.

2.  马逸丹, 常杰*. 长期热量限制延长预期寿命及信号通路的研究述评[J]. 山西医科大学学报, 2020, 51(11): 1273-1276.

3. 常杰. 《职业卫生与职业医学》教学方法改革探索与实践[J]. 教育教学论坛, 2018(36): 91-92.

4.  常杰. 微课结合PBL案例教学在《预防医学》课程中的探索[J]. 教育现代化, 2017, 4(39): 175-176.

会议论文:

1.  Sahoko Ichihara; Jie Chang; Saeko Tada-Oikawa; Chisa Ando; Kentaro Kuzuya; Gaku Ichihara; Shinji Oikawa. Oxidative modification leads to the left ventricular dysfunction in cardiomyopathy[C]//48th Congress of European Societies of Toxicology. 2012-06-17/20.

荣誉奖励：

1.苏州大学本科优秀毕业设计指导老师（2016）。

2.第二届苏州大学教师教学创新大赛特等奖（2022）。

3.苏州大学交通银行奖教金（2023）。

4.江苏省高等学校劳动教育优秀实践项目一等奖（2023）。