张冬梅，女，博士，研究员，博士生导师。暨南大学药学院常务副院长。国家万人计划青年拔尖人才、教育部新世纪优秀人才、广东省青年珠江学者、广东省自然科学基金杰出青年科学基金获得者。担任广东省药理学会副理事长、世界中医药学会联合会肿瘤精准医学专业委员会常务理事、中国药理学会理事、广东省药理学会肿瘤药理专委会副主委、广东省药理学会药物筛选与评价专委会副主委、广东省药学会中药学专业委员会副主委、广东省中西医结合学会中药专业委员会副主委、中国抗癌协会抗肿瘤药物专业委员会常务委员、广东省病理生理学会肿瘤专业委员会委员、广东省本科高校药学类专业教学指导委员会委员、广东省女科技工作者联合会理事。还兼任《Acta Pharm Sin B》、《Front Cell Dev Biol》等十余个杂志的客座主编、编委和青年编委。
从事肿瘤药理学研究和新药研发。先后主持国家重大新药创制专项课题（2项）、国家自然科学基金（3项）、广东省自然科学基金等省部级以上项目10余项。发表SCI论文110余篇，其中以第一或通讯作者在J Clin Invest、J Extracell Vesicles、Mol Cancer、Adv Sci、Drug Res Update、Signal Transduct Target Ther等权威杂志发表SCI论文60余篇，参编英文著作2部。参编国家级规划教材2部。获授权国际发明专利13项，中国发明专利12项，其中7项专利已转化。主持新型抗肿瘤药物临床前研究1项。获国家科学技术进步奖二等奖1项、广东省科学技术奖一等奖3项、第十四届广东省丁颖科技奖、第十二届广东省三八红旗手标兵。
教育及工作经历：
2000年毕业于中国药科大学，获学士学位；
2003年毕业于中国药科大学药物化学专业，获硕士学位；
2007年毕业于香港中文大学生物化学系，获博士学位；
2008年初进入暨南大学药学院工作。
主要学术兼职：
（1）担任广东省药理学会第九届理事会副理事长
（2）担任中国药理学会第十二届理事会理事
（3）担任世界中医药学会联合会肿瘤精准医学专业委员会常务理事
（4）担任中国抗癌协会抗癌药物专业委员会常务委员
（5）担任中国抗癌协会肿瘤标志专业委员会外泌体技术专家委员会常务委员
（6）担任广东省药理学会肿瘤药理专业委员会副主任委员
（7）担任广东省药学会中药专业委员会副主任委员
（8）担任广东省药理学会药物筛选与评价专委会副主委
（9）广东省中西医结合学会中药专业委员会副主委
（10）担任广东省本科高校药学类专业教学指导委员会委员
（11）广东省女科技工作者联合会理事
讲授课程：
（1）《天然活性成分分离和活性筛选》
（2）《药理学》
（3）《分子药理学》
（4）《中药药理学》
（1）中药和天然药物的抗肿瘤活性成分筛选、作用机制研究以及相关创新药物的研发
（2）周细胞介导肿瘤耐药和转移的新机制研究和周细胞靶向药物研发
代表性科研项目：
（1）科技部第四批国家计划
（2）国家科技重大专项重大新药创制项目（编号：2018ZX09711001-008-008）
（3）国家科技重大专项重大新药创制项目：PI3K/mTOR靶向抗肿瘤候选药物BBGV-45研究（编号：2012ZX09103101-053）
（4）国家自然科学基金面上项目（编号：81973340）
（5）国家自然科学基金面上项目（编号：81573455）
（6）国家自然科学基金青年项目：基于靶标Akt研究点地梅中三萜皂苷成分抗肝癌活性的构效关系及作用机制（编号：30901847）
（7）广东省自然科学基金面上项目（编号：2022A1515011813）
（8）广东省基金项目（编号：S2013050014183）
（9）广州市重大科技计划专项子项目：抗肿瘤候选新药沙蟾毒精的研究开发(编号：2011Y1-00017-11)
（10）广州市珠江科技新星专项：靶向PI3K/mTOR的抗肿瘤新药Arenobufagin的研究开发（编号：2011J2200045）
（11）广东省自然科学基金：基于钠钾ATP酶靶标研究新型蟾毒内酯化合物抗肿瘤活性构效关系及作用机制（项目编号：9451063201002969，主持人）
国外专利：
[1]Ye WC, Chen HR, Zhang DM, Chen MF, Xu NH. Vinca Alkaloid Derivatives, Preparation Method therefor and Application thereof. US patent, US10,377,774B2 ；Australia patent, AU2014253584 B2 ；Japan patent, JP6250710；European patent, EP2987794；Germany patent, DE602014026358.5；French patent, FR2987794；British patent, UK2987794； India patent, ID342171
[2]Zhang Dongmei, Chen Minfeng, Ye Wencai, Pan Jinghua, Li Yong, Liu Tongzheng, Qi Qi. Tumor Pericytes, isolation method therefor and use thereof. PCT patent, PCT/CN2020/130723
发明公开：
[1]邓丽娟, 张冬梅, 朱晓峰, 杨钦河, 陈敏锋, 齐明, 黄茂华, 李啸波, 王晨然, 张君秋, 张铭宵, 杨福芹. 一种用于肿瘤辅助治疗的中药组合物及其制备方法和应用[P]. 广东省: CN120713993A, 2025-09-30.
[2]叶文才, 王磊, 张冬梅, 刘俊珊, 范春林, 曹佳青. 一类促进组织修复的新多肽及其应用[P]. 广东省: CN117659124A, 2024-03-08.
[3]齐明, 范舒然, 陈敏锋, 陈敏珊, 张铭宵, 叶文才, 张冬梅. 一种血管化类器官的构建方法与应用[P]. 广东省: CN116836911A, 2023-10-03.
[4]张冬梅, 曹义海, 叶文才, 张章, 陈敏锋, 黄茂华, 王生, 叶格妮, 邓丽娟. 一种周细胞靶向NNMT抑制剂在制备抗肿瘤转移药物中的应用[P]. 广东省: CN116808213A, 2023-09-29.
[5]陈敏锋, 张冬梅, 叶文才, 齐明, 范舒然, 张君秋. 一种长春碱类衍生物在制备治疗淋巴结转移药物中的应用[P]. 广东省: CN116549596A, 2023-08-08.
[6]张冬梅, 叶文才, 陈敏锋, 齐琦, 黄茂华, 邓丽娟. 23-羟基白桦酸衍生物在制备HSPB8抑制剂中的应用[P]. 广东省: CN115998751A, 2023-04-25.
[7]叶文才, 王磊, 张冬梅, 刘俊珊, 范春林, 曹佳青. 一类促进组织修复的新多肽及其应用[P]. 广东省: CN114478695A, 2022-05-13.
[8]张冬梅, 陈敏锋, 叶文才, 潘京华, 李勇, 刘同征, 齐琦. 一种肿瘤血管周细胞及其分离方法与应用[P]. 广东省: CN113667629A, 2021-11-19.
[9]陈敏锋, 张冬梅, 陈河如, 叶文才, 李勇, 黄茂华, 叶格妮, 范春林. 长春碱类衍生物在制备治疗骨肉瘤和/或软组织肉瘤药物中的应用[P]. 广东省: CN113456797A, 2021-10-01.
[10]张晓琦, 叶文才, 张冬梅, 李勇, 敖运林. 一种双吲哚生物碱化合物及其合成方法和用途[P]. 广东省: CN113248524A, 2021-08-13.
[11]张晓琦, 叶文才, 张冬梅. 狗牙花属植物提取物及其提取分离方法和用途[P]. 广东省: CN113248525A, 2021-08-13.
[12]叶文才, 王英, 胡利军, 唐维, 李药兰, 张冬梅, 范春林. 一类多环聚酮化合物在制备抗新型冠状病毒药物中的应用[P]. 广东省: CN112741831A, 2021-05-04.
[13]张冬梅, 陈河如, 叶文才. 长春碱类衍生物在制备抑制肿瘤转移药物中的应用[P]. 广东省: CN112603989A, 2021-04-06.
[14]张冬梅, 叶文才, 陈卫民, 姚楠, 李英杰, 雷雨禾, 胡楠, 蓝平, 王龙海. 23-羟基白桦酸衍生物在制备EGFR激动剂中的应用[P]. 广东省: CN110237082A, 2019-09-17.
[15]张冬梅, 陈河如, 叶文才, 陈敏锋, 李啸波, 雷雪萍. 长春碱类衍生物在制备抑制肿瘤转移药物中的应用[P]. 广东: CN107349415A, 2017-11-17.
[16]丁克, 耿美玉, 谈理, 丁健, 张章, 艾菁, 任小梅, 高冬林, 涂正超, 陆小云, 张冬梅. 取代喹诺酮类衍生物或其药学上可接受的盐或立体异构体及其药用组合物和应用[P]. 广东: CN106467541A, 2017-03-01.
[17]叶文才, 陈河如, 张冬梅, 陈敏峰, 许男徽. 长春碱类衍生物及其制备方法和应用[P]. 广东: CN105121447A, 2015-12-02.
[18]叶文才, 王磊, 张冬梅, 李宝晶. 一种新的19-脱甲基蟾毒内酯化合物及其在制备抗肿瘤药物制剂中的应用[P]. 广东: CN104892721A, 2015-09-09.
[19]叶文才, 张冬梅, 陈河如, 陈敏锋, 肖绪枝, 许男徽, 雷雪萍, 胡坚杨. 长春碱及其类似物的新应用[P]. 广东: CN104740602A, 2015-07-01.
[20]陈河如, 叶文才, 张冬梅, 陈敏锋, 肖绪枝, 许男徽, 雷雪萍, 胡坚杨. 一种吲哚生物碱加合物及其制备方法和在制备抗肿瘤药物中的应用[P]. 广东: CN103275106A, 2013-09-04.
[21]陈河如, 张冬梅, 叶文才, 郑晶, 陈敏锋, 白亮亮, 邓丽娟. 一种乙烯桥连吲哚化合物及其合成方法和用途[P]. 广东: CN102942515A, 2013-02-27.
[22]叶文才, 张冬梅, 王英, 范春林, 李勇, 巫鑫. 木豆素在制备治疗或预防股骨头坏死药物中的应用[P]. 广东: CN102755309A, 2012-10-31.
[23]李药兰, 叶文才, 王国才, 王英, 张晓琦, 张冬梅. 咖啡酰衍生物及其在制备抗呼吸道合胞病毒药物中的用途[P]. 广东: CN102219686A, 2011-10-19.
[24]李药兰, 叶文才, 吴霞, 王国才, 王英, 张晓琦, 张冬梅. 地胆草提取物及其制备方法和在制备抗病毒药物中的用途[P]. 广东: CN102219687A, 2011-10-19.
[25]张晓琦, 叶文才, 叶春玲, 赵晶晶, 范春林, 王英, 邵萌, 张建, 张冬梅. 具有降血糖作用的番石榴叶提取物及其制备方法与应用[P]. 广东: CN102178741A, 2011-09-14.
[26]叶文才, 陈卫民, 蓝平, 张冬梅, 王娇, 舒畅, 曹惠慧, 于淼. 23-羟基白桦酸衍生物及其制备方法和用途[P]. 广东: CN102108092A, 2011-06-29.
[27]叶文才, 张冬梅, 刘俊珊, 曹惠慧, 田海妍. 沙蟾毒精在制备抗肿瘤药物制剂中的应用[P]. 广东: CN102038690A, 2011-05-04.
发明授权：
[1]陈敏锋, 张冬梅, 陈河如, 叶文才, 李勇, 黄茂华, 叶格妮, 范春林. 长春碱类衍生物在制备治疗骨肉瘤和/或软组织肉瘤药物中的应用[P]. 广东省: CN113456797B, 2024-03-08.
[2]叶文才, 王磊, 张冬梅, 刘俊珊, 范春林, 曹佳青. 一类促进组织修复的新多肽及其应用[P]. 广东省: CN114478695B, 2024-01-23.
[3]张冬梅, 陈敏锋, 叶文才, 潘京华, 李勇, 刘同征, 齐琦. 一种肿瘤血管周细胞及其分离方法与应用[P]. 广东省: CN113667629B, 2023-10-13.
[4]张晓琦, 叶文才, 张冬梅. 狗牙花属植物提取物及其提取分离方法和用途[P]. 广东省: CN113248525B, 2022-10-18.
[5]张晓琦, 叶文才, 张冬梅, 李勇, 敖运林. 一种双吲哚生物碱化合物及其合成方法和用途[P]. 广东省: CN113248524B, 2022-08-05.
[6]叶文才, 王英, 胡利军, 唐维, 李药兰, 张冬梅, 范春林. 一类多环聚酮化合物在制备抗新型冠状病毒药物中的应用[P]. 广东省: CN112741831B, 2022-07-19.
[7]叶文才, 张冬梅, 陈河如, 陈敏锋, 肖绪枝, 许男徽, 雷雪萍, 胡坚杨. 长春碱及其类似物的应用[P]. 广东省: CN104740602B, 2018-10-30.
[8]叶文才, 陈河如, 张冬梅, 陈敏峰, 许男徽. 长春碱类衍生物及其制备方法和应用[P]. 广东省: CN105121447B, 2018-02-02.
[9]叶文才, 王磊, 张冬梅, 李宝晶. 一种新的19-脱甲基蟾毒内酯化合物及其在制备抗肿瘤药物制剂中的应用[P]. 广东省: CN104892721B, 2016-09-07.
[10]陈河如, 叶文才, 张冬梅, 陈敏锋, 肖绪枝, 许男徽, 雷雪萍, 胡坚杨. 一种吲哚生物碱加合物及其制备方法和在制备抗肿瘤药物中的应用[P]. 广东省: CN103275106B, 2015-09-30.
[11]叶文才, 陈卫民, 蓝平, 张冬梅, 王娇, 舒畅, 曹惠慧, 于淼. 23-羟基白桦酸衍生物及其制备方法和用途[P]. 广东省: CN102108092B, 2014-07-02.
[12]叶文才, 张冬梅, 王英, 范春林, 李勇, 巫鑫. 木豆素在制备治疗或预防股骨头坏死药物中的应用[P]. 广东省: CN102755309B, 2014-03-05.
[13]李药兰, 叶文才, 吴霞, 王国才, 王英, 张晓琦, 张冬梅. 地胆草提取物及其制备方法和在制备抗病毒药物中的用途[P]. 广东省: CN102219687B, 2013-09-04.
[14]张晓琦, 叶文才, 叶春玲, 赵晶晶, 范春林, 王英, 邵萌, 张建, 张冬梅. 具有降血糖作用的番石榴叶提取物及其制备方法与应用[P]. 广东省: CN102178741B, 2013-01-16.
[15]叶文才, 张冬梅, 刘俊珊, 曹惠慧, 田海妍. 沙蟾毒精在制备抗肿瘤药物制剂中的应用[P]. 广东省: CN102038690B, 2012-07-11.
发表期刊论文：
1 Ran Y#, Xu ZY#,Chen MF#, Wang W#, Wu Y, Cai JX, Long JQ, Chen ZS, Zhang DM*, Guan BO*. Fiber-Optic theranostics (FOT): interstitial fiber-optic needles for cancer sensing and therapy. Adv Sci. 2022, e2200456.
2 Fan, Shu-Ran#; Deng, Wei-Qing#; Deng, Li-Juan#; Chen, Min-Feng; Qi, Ming; Lyu, Wen-Yu; Qi, Qi; Tiwari, Amit K.; Chen, Jia-Xu*; Zhang, Dong-Mei*; Chen, Zhe-Sheng*.m6A modification: recent advances, anticancer targeted drug discovery and beyond.Molecular Cancer, 2022, 21(1): 52.
3 Huang MH#, Li YN#, Wang CR#, Deng LJ, Chen MF, Assaraf Yehuda G, Chen ZS*, Ye WC*, Zhang DM*. New insights into antiangiogenic therapy resistance in cancer: mechanisms and therapeutic aspects. Drug Resist Update. 2022.
4 Ye GN#, Huang MH#, Li Y, Ouyang J, Chen MF, Wen Q, Li XB, Zeng HH, Long P, Fan ZP, Yin JQ*, Ye WC*, Zhang DM*. The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway. Acta Pharmaceutica Sinica B. 2022, 12（3）：1288-1304.
5 Huang, Maohua; Chen, Minfeng; Qi, Ming; Ye, Geni; Pan, Jinghua; Shi, Changzheng; Yang, Yunlong; Zhao, Luyu; Mo, Xukai; Zhang, Yiran; Li, Yong; Zhong, Jincheng; Lu, Weijin; Li, Xiaobo; Zhang, Jiayan; Lin, Jinrong; Luo, Liangping; Liu, Tongzheng; Tang, Patrick Ming-Kuen; Hong, An; Cao, Yihai*; Ye, Wencai*; Zhang, Dongmei*.Perivascular cell-derived extracellular vesicles stimulate colorectal cancer revascularization after withdrawal of antiangiogenic drugs.Journal of Extracellular Vesicles, 2021, 10(7): e12096.
6 Li, Xiaobo; Chen, Minfeng; Lu, Weijin; Tang, Jun; Deng, Lijuan; Wen, Qing; Huang, Maohua; Deng, Rong; Ye, Geni; Ye, Wencai*; Zhang, Dongmei*.Targeting FAP alpha-expressing tumor-associated mesenchymal stromal cells inhibits triple-negative breast cancer pulmonary metastasis.Cancer Letters, 2021, 503: 32-42.
7 Long, Pei; Li, Yong; Wen, Qing; Huang, Maohua; Li, Songtao; Lin, Yuning; Huang, Xiaojun; Chen, Minfeng; Ouyang, Jie; Ao, Yunlin; Qi, Qi; Zhang, Haipeng; Ye, Wencai; Cheng, Guohua*; Zhang, Xiaoqi*; Zhang, Dongmei*.3 '-Oxo-tabernaelegantine A (OTNA) selectively relaxes pulmonary arteries by inhibiting AhR.Phytomedicine, 2021, 92: 153751.
8 Deng, Li-Juan; Lei, Yu-He; Quan, Jing-Yu; Li, Bao-Jing; Zhang, Dong-Mei; Tian, Hai-Yan; Chen, Ye; Zhang, En-Xin; Chen, Lei; Ye, Wen-Cai; Ning, Wei-Min; Yu, Lin-Zhong*; Liu, Jun-Shan*.1 beta-OH-arenobufagin induces mitochondrial apoptosis in hepatocellular carcinoma through the suppression of mTOR signaling pathway.Journal of Ethnopharmacology, 2021, 266: 113443.
9 Ye, G.; Huang, M.; Li, Y.; Ouyang, J.; Zhang, D..The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway.Acta Pharmaceutica Sinica B, 2021.
10 Deng Li Juan; Lei Yu He; Quan Jing Yu; Li Bao Jing; Zhang Dong Mei; Tian Hai Yan; Chen Ye; Zhang En Xin; Chen Lei; Ye Wen Cai; Ning Wei Min; Yu Lin Zhong; Liu Jun Shan.1β–OH–arenobufagin induces mitochondrial apoptosis in hepatocellular carcinoma through the suppression of mTOR signaling pathway.Journal of Ethnopharmacology, 2021, 266.
11 Zhang, Jian; Song, Min; Ao, Yun-Lin; Li, Yong; Zou, Xue-Yi; Xu, Jie; Wang, Ying; Zhang, Dong-Mei; Zhang, Xiao-Qi*; Ye, Wen-Cai*.Alstolarines A and B, two unusual monoterpenoid indole alkaloids with an acetal moiety from Alstonia scholaris.Organic Chemistry Frontiers, 2020, 7(21): 3468-3473.
12 Zhong, Jincheng; Lu, Weijin; Zhang, Jiayan; Huang, Maohua; Lyu, Wenyu; Ye, Geni; Deng, Lijuan; Chen, Minfeng; Yao, Nan; Li, Yong; Liu, Guanping; Liang, Yunfei; Fu, Jingwen; Zhang, Dongmei*; Ye, Wencai*.Notoginsenoside R1 activates the Ang2/Tie2 pathway to promote angiogenesis.Phytomedicine, 2020, 78: 153302.
13 Li-Juan, Deng; Yong, Li; Ming, Qi; Jun-Shan, Liu; Sheng, Wang; Li-Jun, Hu; Yu-He, Lei; Ren-Wang, Jiang; Wei-Min, Chen; Qi; Hai-Yan, Tian; Wei-Li, Han; Bao-Jian, Wu; Jia-Xu, Chen; Wen-Cai, Ye; Dong-Mei, Zhang.Molecular mechanisms of bufadienolides and their novel strategies for cancer treatment.European Journal of Pharmacology, 2020, 887: 173379.
14 Zheng, Yuanru; Deng, Lijuan; Cao, Huihui; Xu, Nishan; Zhang, Dongmei; Tian, Haiyan; Li, Baojing; Lu, Zibin; Ye, Wencai; Yu, Linzhong*; Fan, Chunlin*; Liu, Junshan*.Screening of Bufadienolides from Toad Venom Identifies Gammabufotalin as a Potential Anti-inflammatory Agent.Planta Medica, 2020.
15 Yao, Nan; Wang, Chen-Ran; Liu, Ming-Qun; Li, Ying-Jie; Chen, Wei-Min; Li, Zheng-Qiu; Qi, Qi; Lu, Jin-Jian; Fan, Chun-Lin; Chen, Min-Feng; Qi, Ming; Li, Xiao-Bo; Hong, Jian; Zhang, Dong-Mei*; Ye, Wen-Cai*.Discovery of a novel EGFR ligand DPBA that degrades EGFR and suppresses EGFR-positive NSCLC growth.Signal Transduction and Targeted Therapy, 2020, 5(1): 214.
16 Jin-Cheng, ZHONG; Xiao-Bo, LI; Wen-Yu, LYU; Wen-Cai, YE; Dong-Mei, ZHANG.Natural products as potent inhibitors of hypoxia-inducible factor-1α in cancer therapy.Chinese Journal of Natural Medicines, 2020, 18(9): 696-703.
17 Gan, Hua; Qi, Ming; Chan, Chakpiu; Leung, Pan; Ye, Geni; Lei, Yuhe; Liu, Aiai; Xue, Feifei; Liu, Dongdong; Ye, Wencai; Zhang, Dongmei; Deng, Lijuan; Chen, Jiaxu.Digitoxin inhibits HeLa cell growth through the induction of G(2)/M cell cycle arrest and apoptosisin vitroandin vivo.International Journal of Oncology, 2020, 57(2): 562-573.
18 He, Jun; Hu, Lijun; Huang, Xiaojun; Wang, Chenran; Zhang, Zhimin; Wang, Ying; Zhang, Dongmei; Ye, Wencai.Potential of coronavirus 3C-like protease inhibitors for the development of new anti-SARS-CoV-2 drugs: Insights from structures of protease and inhibitors.International Journal of Antimicrobial Agents, 2020, 56(2): 106055.
19 Wei, Xia; Feng, Chan; Wang, Si-Yu; Zhang, Dong-Mei; Li, Xiao-Hui*; Zhang, Cui-Xian*.New Indole Diketopiperazine Alkaloids from Soft Coral-Associated Epiphytic Fungus Aspergillus sp. EGF 15-0-3.Chemistry and Biodiversity, 2020, 17(5).
20 Ma, Nan; Zhang, Zhi-Min; Lee, Jun-Seok; Cheng, Ke; Lin, Ligen; Zhang, Dong-Mei; Hao, Piliang*; Ding, Ke*; Ye, Wen-Cai*; Li, Zhengqiu*.Affinity-Based Protein Profiling Reveals Cellular Targets of Photoreactive Anticancer Inhibitors.ACS Chemical Biology, 2019, 14(12): 2546-2552.
21 Zhang Jian; Li Hua; Li Yong; Li Zi-Wei; Sang Chen-Chen; Gao Mei-Hua; Zhang Dong-Mei; Zhang Xiao-Qi*; Ye Wen-Cai*.Four new corynanthe-type alkaloids from the roots of Alstonia scholaris.Chinese Journal of Natural Medicines, 2019, 17(12): 918-923.
22 Deng, Li Juan; Lei, Yu He; Chiu, Tsz Fung; Qi, Ming; Gan, Hua; Zhang, Ge; Peng, Zhi Da; Zhang, Dong Mei; Chen, Yan Fen*; Chen, Jia Xu*.The Anticancer Effects of Paeoniflorin and Its Underlying Mechanisms.Natural Product Communications, 2019, 14(9).
23 Liang, Jianye; Cheng, Qingqing; Huang, Jiaxi; Ma, Mengjie; Zhang, Dong; Lei, Xueping; Xiao, Zeyu; Zhang, Dongmei*; Shi, Changzheng*; Luo, Liangping*.Monitoring tumour microenvironment changes during anti-angiogenesis therapy using functional MRI.Angiogenesis, 2019, 22(3): 457-470.
24 Yuan, Mengfei; Ao, Yunlin; Yao, Nan; Xie, Jing; Zhang, Dongmei; Zhang, Jian*; Zhang, Xiaoqi*; Ye, Wencai.Two New Flavonoids from the Nuts of Areca catechu.Molecules, 2019, 24(16): 2862.
25 Wei, Xia; Feng, Chan; Li, Xiao Hui; Mao, Xing Xin; Luo, Hai Bin; Zhang, Dong Mei; Rong, Li; Xie, Zhen Yu; Yu, Xin; Li, Jie; Ye, Wen Cai; Huang, Xiao Jun*; Zhang, Cui Xian*.Enantiomeric Polyketides from the Starfish-Derived Symbiotic Fungus Penicillium sp. GGF16-1-2.Chemistry and Biodiversity, 2019, 16(6): e1900052.
26 Zhang, Jiayan; Liu, Mingqun; Huang, Maohua; Chen, Minfeng; Zhang, Dong; Luo, Liangping; Ye, Geni; Deng, Lijuan; Peng, Yinghui; Wu, Xin; Liu, Guanping; Ye, Wencai*; Zhang, Dongmei*.Ginsenoside F1 promotes angiogenesis by activating the IGF-1/IGF1R pathway.Pharmacological Research, 2019, 144: 292-305.
28 Liang, Qiu Ping; Xu, Tian Qi; Liu, Bai Lian; Lei, Xue Ping; Hambrook, Jacob R; Zhang, Dong Mei; Zhou, Guang Xiong*.Sasanquasaponin III from Schima crenata Korth induces autophagy through Akt/mTOR/p70S6K pathway and promotes apoptosis in human melanoma A375 cells.Phytomedicine, 2019, 58: 152769.
29 Liang, Jianye; Mae, Rong; Chen, Heru; Zhang, Dongmei; Ye, Wencai; Shi, Changzheng; Luo, Liangping*.Detection of Hyperacute Reactions of Desacetylvinblastine Monohydrazide in a Xenograft Model Using Intravoxel Incoherent Motion DWI and R2*Mapping.American Journal of Roentgenology, 2019, 212(4): 717-726.
30 Liu, Jun-Shan; Deng, Li-Juan; Tian, Hai-Yan; Ruan, Zhi-Xiong; Cao, Hui-Hui; Ye, Wen-Cai; Zhang, Dong-Mei*; Yu, Zhi-Ling*.Anti-tumor effects and 3D-quantitative structure-activity relationship analysis of bufadienolides from toad venom.Fitoterapia, 2019, 134: 362-371.
31 Yao, Nan; Wang, Chenran; Hu, Nan; Li, Yingjie; Liu, Mingqun; Lei, Yuhe; Chen, Minfeng; Chen, Liping; Chen, Chen; Lan, Ping; Chen, Weimin; Chen, Zhesheng; Fu, Dengrui; Ye, Wencai; Zhang, Dongmei*.Inhibition of PINK1/Parkin-dependent mitophagy sensitizes multidrug-resistant cancer cells to B5G1, a new betulinic acid analog.Cell Death & Disease, 2019, 10(3): 232.
32 Chen, Bo; Liu, Xin; Hu, Ya-Jian; Zhang, Dong-Mei; Deng, Lijuan; Lu, Jieyu; Min, Long; Ye, Wen-Cai; Li, Chuang-Chuang* Enantioselective total synthesis of (-)-colchicine, (+)-demecolcinone and metacolchicine: determination of the absolute configurations of the latter two alkaloids (vol 8, pg 4961, 2017) Chemical Science, 2019, 10(3): 946-946.
33 Liu, Zhi-Wen; Zhang, Jian; Li, Song-Tao; Liu, Ming-Qun; Huang, Xiao-Jun; Ao, Yun-Lin; Fan, Chun-Lin; Zhang, Dong-Mei; Zhang, Qing-Wen; Ye, Wen-Cai*; Zhang, Xiao-Qi*.Ervadivamines A and B, Two Unusual Trimeric Monoterpenoid Indole Alkaloids from Ervatamia divaricata.Journal of Organic Chemistry, 2018, 83(17): 10613-10618.
34 Zhu Xuelin; Ye Qinmei; Wen Chao; Chen Liping; Liang Guangping; Zeng Ting; Zhang Dongmei*; Jiang Renwang*.Synthesis of Camptothecin-10-O-glucoside Using an Engineered Oleandomycin Glucosyltransferase.Chemical Research in Chinese Universities, 2018, 34(3): 423-427.
35 Chen LP; Zhang DM*.Reflection on the selection of doses of arenobufagin in vivo anticancer study.Pharmacological Research, 2018, 128(1): 402.
36 Lei XP#; Chen MF#; Li XB; Huang MH; Nie QL; Ma N; Chen HR; Xu NH; Ye WC*; Zhang DM*.A vascular disrupting agent overcomes tumor multidrug resistance by skewing macrophage polarity toward the M1 phenotype.Cancer Letters, 2018, 418: 239-249.
37 Lei XP#; Chen MF#; Huang MH; Li XB; Shi CZ; Zhang D; Luo LP; Zhang YW; Ma N; Chen HR; Liang HF; Ye WC*; Zhang DM*.Desacetylvinblastine Monohydrazide Disrupts Tumor Vessels by Promoting VE-cadherin Internalization.Theranostics, 2018, 8(2): 384-398.
38 Chen MF#, Lei XP#, Shi CZ, Huang MH, Li XB, Wu BJ, Li ZQ, Han WL, Du B, Hu JY, Nie QL, Mai WQ, Ma N, Xu NH, Zhang XY, Fan CL, Hong AH, Xia MH, Luo LP, Ma AD, Li HS, Yu Q, Chen HR*, Zhang DM*, Ye WC*. Pericyte-targeting prodrug overcomes tumor resistance to vascular disrupting agents. The Journal of Clinical Investigation. 2017, 127(10):3689-3701.
40 Sun HY#; Huang MH#; Yao N#; Hu JY; Li YJ; Chen LP; Hu N; Ye WC; Tai CS; Zhang DM*; Chen SB*.The cycloartane triterpenoid ADCX impairs autophagic degradation through Akt overactivation and promotes apoptotic cell death in multidrug-resistant HepG2/ADM cells.Biochemical Pharmacology, 2017, 146: 87-100.
41 Chen LP#; Mai WQ#; Chen MF; Hu JY; Zhuo ZJ; Lei XP; Deng LJ; Liu JS; Yao N; Haung MH; Peng YH; Ye WC*; Zhang DM*.Arenobufagin inhibits prostate cancer epithelial-mesenchymal transition and metastasis by down-regulating β-catenin.Pharmacological Research, 2017, 123: 130-142.
42 Liping Chen; Weiqian Mai; Minfeng Chen; Jianyang Hu; Zhenjian Zhuo; Xueping Lei; Lijuan Deng; Junshan Liu; Nan Yao; Maohua Huang; Yinghui Peng; Wencai Ye; Dongmei Zhang.Arenobufagin inhibits prostate cancer epithelial-mesenchymal transition and metastasis by down-regulating β-catenin.Pharmacological Research, 2017, 123: 130-142.
43 Deng LJ#; Wang LH#; Peng CK; Li YB; Huang MH; Chen MF; Lei XP; Qi M; Cen Y; Ye WC*; Zhang DM*; Chen WM*.Fibroblast Activation Protein α Activated Tripeptide Bufadienolide Antitumor Prodrug with Reduced Cardiotoxicity.Journal of Medicinal Chemistry, 2017, 60(13): 5320-5333.
44 Kuok, Chiu-Fai; Zhang, Jian; Fan, Chun-Lin; Zhang, Qing-Wen; Fan, Run-Zhu; Zhang, Dong-Mei; Zhang, Xiao-Qi*; Ye, Wen-Cai*.Meloslines A and B, two novel indole alkaloids from Alstonia scholaris.Tetrahedron Letters, 2017, 58(28): 2740-2742.
45 Chen B#; Liu X#; Hu YJ; Zhang DM; Deng LJ; Lu JY; Min L; Ye WC; Li CC*.Enantioselective total synthesis of (-)-colchicine, (+)-demecolcinone and metacolchicine: determination of the absolute configurations of the latter two alkaloids.Chemical Science, 2017, 8(7): 4961-4966.
46 Li YJ#; Lei YH#; Yao N; Wang CR; Hu N; Ye WC; Zhang DM*; Chen ZS*.Autophagy and multidrug resistance in cancer.Chinese Journal of Cancer, 2017, 36: 52.
47 Li XB#; Chen MF#; Lei XP; Huang MH; Ye WC; Zhang RJ*; Zhang DM*.Luteolin inhibits angiogenesis by blocking Gas6/Axl signaling pathway, International Journal of Oncology, 2017.6.13, 51(2): 677~685
48 Huang BY; Zeng Y; Li YJ; Huang XJ; Hu N; Yao N; Chen MF; Yang ZG; Chen ZS; Zhang DM*; Zeng CQ*.Uncaria alkaloids reverse ABCB1-mediated cancer multidrug resistance, International Journal of Oncology, 2017.5.17, 51(1): 257~268
49 Zhang YK; Zhang XY; Zhang GN; Wang YJ; Xu H; Zhang DM; Shukla S; Liu L; Yang DH; Ambudkar SV; Chen ZS*.Selective reversal of BCRP-mediated MDR by VEGFR-2 inhibitor ZM323881, Biochemical Pharmacology, 2017.5.15, 132: 29~37
50 Yin ZQ*; Wang L; Li CH; Zhang DM; Zhang W; Wang Y; Zhao M; Che CT; Ye WC.New triterpene saponins from the aerial parts of Androsace umbellata.RSC advances, 2017, 7(41): 25765-25772.
51 Zhang W#; Zhang SY#; Wang GY; Li NP; Chen MF; Gu JH; Zhang DM; Wang L*; Ye WC*.Five new koumine-type alkaloids from the roots of Gelsemium elegans.Fitoterapia, 2017, 118: 112-117.
52 Wang, Gui-Yang; Wang, Ai-Ting; Zhao, Bing-Xin; Lei, Xue-Ping; Zhang, Dong-Mei; Jiang, Ren-Wang; Wang, Ying*; Ye, Wen-Cai*.Norsecurinamines A and B, two norsecurinine-derived alkaloid dimers from the fruits of Flueggea virosa.Tetrahedron Letters, 2016, 57(34): 3810-3813.
53 Liu C; Ang S; Huang XJ; Tian HY; Deng YY; Zhang DM; Wang Y; Ye WC; Wang L.Meroterpenoids with New Skeletons from Myrtus communis and Structure Revision of Myrtucommulone K.Organic Letters, 2016, 18(16): 4004-4007.
54 Lei X; Chen M; Nie Q; Hu J; Zhuo Z; Yiu A; Chen H; Xu N; Huang M; Ye K; Bai L; Ye W; Zhang D.In vitro and in vivo antiangiogenic activity of desacetylvinblastine monohydrazide through inhibition of VEGFR2 and Axl pathways.American Journal of Cancer Research, 2016, 6(4): 843-58.
55 Li, Yu-Ting; Gao, Xian-Da; Zhang, Wei; Huang, Xiao-Jun; Zhang, Dong-Mei; Jiang, Ren-Wang; Wang, Lei*; Zhang, Xiao-Qi*; Ye, Wen-Cai*.Winchinines A and B, two unusual monoterpene indole alkaloids with a third nitrogen atom from Winchia calophylla.RSC Advances, 2016, 6(64): 59657-59660.
56 Zhang, Peng-Wei; Tian, Hai-Yan; Nie, Qiu-Lin; Wang, Lei; Zhou, Shi-Wen; Ye, Wen-Cai*; Zhang, Dong-Mei*; Jiang, Ren-Wang*.Structures and inhibitory activity against breast cancer cells of new bufadienolides from the eggs of toad Bufo bufo gargarizans.RSC Advances, 2016, 6(96): 93832-93841.
57 Sun HY; Liu BB; Hu JY; Xu LJ; Chan SW; Chan CO; Mok DK; Zhang DM*; Ye WC; Chen SB*.Novel cycloartane triterpenoid from Cimicifuga foetida (Sheng ma) induces mitochondrial apoptosis via inhibiting Raf/MEK/ERKpathway and Akt phosphorylation in human breast carcinoma MCF-7 cells.Chinese Medicine, 2016, 11: 1-11.
58 Hu JY; Chen MF; Lei XP; Zhuo ZJ; Sun HY; Chen ZS; Shi Z; Zhang DM*; Ye WC*.Bufalin induces apoptosis of MDA-MB-231 cell through activation of JNK/p53 pathway.Journal of Cancer Research Updates, 2015, 4(2): 47-53.
59 Li BJ#; Tian HY,#; Zhang DM; Lei YH; Wang L*; Jiang RW*; Ye WC*.Bufadienolides with cytotoxic activity from the skins of Bufo bufo gargarizans.Fitoterapia, 2015, 105: 7-15.
60 Jian YQ#; Huang XJ#; Zhang DM; Jiang RW; Chen MF; Zhao BX; Wang Y*; Ye WC*.Guapsidial A and Guadials B and C: three new meroterpenoids with unusual skeletons from the leaves of Psidium guajava.Chemistry-A European Journal, 2015, 21(25): 9922-7.
61 Zhang W#; Huang XJ#; Zhang SY; Zhang DM; Jiang RW; Hu JY; Zhang XQ; Wang L*; Ye WC*.Geleganidines A-C, unusual monoterpenoid indole alkaloids from gelsemium elegans.Journal of Natural Products, 2015, 78(8): 2036-44.
62 Ye QM#; Bai LL#; Hu SZ#; Tian HY; Ruan LJ; Tan YF; Hu LP; Ye WC; Zhang DM*; Jiang RW*.Isolation, chemotaxonomic significance and cytotoxic effects of quassinoids from Brucea javanica.Fitoterapia, 2015, 105: 66-72.
63 Yao N#; Li YJ#; Zhang DM*; Liu DL; Tang MK; Yiu A; Li Y; Chen WM; Lan P; Yao Z; Chen ZS; Ye WC*.B4G2 induces mitochondrial apoptosis by the ROS-mediated opening of Ca2+-dependent permeability transition pores.Cellular Physiology and Biochemistry, 2015, 37(3): 838-52.
64 Liu DL#; Li YJ#; Yang DH; Wang CR; Xu J; Yao N; Zhang XQ; Chen ZS; Ye WC*; Zhang DM*.Ganoderma lucidum derived ganoderenic acid B reverses ABCB1-mediated multidrug resistance in HepG2/ADM cells.International Journal of Oncology, 2015, 46(5): 2029-38.
65 Zhuo ZJ#; Hu JY#; Yang XL; Chen MF; Lei XP; Deng LJ; Yao N; Peng QL; Chen ZS; Ye WC*; Zhang DM*.Ailanthone inhibits Huh7 cancer cell growth via cell cycle arrest and apoptosis in vitro and in vivo.Scientific Reports, 2015, 5: 16185-15.
66 Deng LJ#; Peng QL#; Wang LH; Xu J; Liu JS; Li YJ; Zhuo ZJ; Bai LL; Hu LP; Chen WM; Ye WC*; Zhang DM*.Arenobufagin intercalates with DNA leading to G2 cell cycle arrest via ATM/ATR pathway.Oncotarget, 2015, 6(33): 34258-75.
67 Xiang QF#; Zhang DM#; Wang JN; Zhang HW; Zheng ZY; Yu DC; Li YJ; Xu J; Chen YJ*; Shang CZ*.Cabozantinib reverses multidrug resistance of human hepatoma HepG2/adr cells by modulating the function of P-glycoprotein.Liver International, 2015, 35(3): 1010-23.
68 Zhang DM#; Xu HG#; Wang L; Li YJ; Sun PH; Wu XM; Wang GJ; Chen WM*; Ye WC*.Betulinic acid and its derivatives as potential antitumor agents.Medicinal Research Reviews, 2015, 35(6): 1127-55.
69 Tian HY; Zhang PW; Liu JS; Zhang DM; Zhang XQ; Jiang RW*; Ye WC*.New cytotoxic C-3 dehydrated bufadienolides from the venom of Bufo bufo gargarizans.Chinese Chemical Letters, 2014, 25(7): 1104-6.
70 Liu, Dao Lu; Li, Ying Jie; Yao, Nan; Xu, Jun; Chen, Zhe Sheng; Yiu, Anita; Zhang, Cui Xian; Ye, Wen Cai*; Zhang, Dong Mei.Acerinol, a cyclolanstane triterpenoid from Cimicifuga acerina, reverses ABCB1-mediated multidrug resistance in HepG2/ADM and MCF-7/ADR cells.European Journal of Pharmacology, 2014, 733: 34-44.
71 Yang XL#; Wang RF#; Zhang SP; Zhu WJ; Tang J; Liu JF; Chen P*; Zhang DM*; Ye WC; Zheng XL.Polysaccharides from Panax japonicus C.A. Meyer and their antioxidant activities.Carbohydrate Polymers, 2014, 101: 386-391.
72 Yang XL#; Wang RF#; Zhang SP; Zhu WJ; Tang J; Liu JF; Chen P*; Zhang DM*; Ye WC; Zheng YL.Polysaccharides from Panax japonicus C.A. Meyer and their antioxidant activities.Carbohydrate Polymers, 2014, 101: 386-91.
73 Guo CP; Peng QL; Pan L; Zhang DM; Chen HR*. Design and synthesis of pyrazol-bridged simplified vinblastine analogues.Chinese Journal of Organic Chemistry, 2014, 34: 2505-10.
74 孙一蕊; 范春林*; 王贵阳; 王英; 张冬梅; 周杰; 邓海鸣; 叶文才*.消渴丸 HPLC 特征图谱研究.药物分析杂志, 2014, 34(3): 539-46.
75 国翠平; 彭群龙; 潘龙; 张冬梅; 陈河如*.吡唑环桥连简约型长春碱类似物的设计合成.有机化学, 2014, 34(卷): 2505-10.
76 Yao N; Liu DL; Li YJ; Chen ZS; Shi Z; Chen WM; Yao Z; Zhang DM*; Ye WC*.B5H7, a morpholine derivative of 23-Hydroxybetulinic acid, reverses doxorubicin resistance in HepG2/ADM.Journal of Cancer Research Updates, 2014, 3(1): 59-66.
77 Li XL#; Zhao BX#; Huang XJ; Zhang DM; Jiang RW; Li YJ; Jian YQ; Wang Y*; Li YL*; Ye WC*.(+)- and (-)-Cajanusine, a pair of new enantiomeric stilbene dimers with a new skeleton from the leaves of Cajanus cajan.Organic Letters, 2014, 16(1): 224-227.
78 Yang XL; Yuan YL; Zhang DM; Li F*; Ye WC*.Shinjulactone O, a new quassiniod from the root bark of Alanthus altissima.Natural Product Research, 2014, 28(18): 1432-7.
79 Wu XL#; Cheang WS#; Zhang DM*; Li Y; Lau CW; Wang GC; Huang Y*; Ye WC.Antagonism of Ca2+ influx via L-Type Ca2+ channels mediates the vasorelaxant effect of catharanthus roseus-derived vindorosine in rat renal artery.Planta Medica, 2014, 80(18): 1672-7.
80 Lei LF#; Chen MF#; Wang T; He XX; Liu BX; Deng Y; Chen XJ; Li YT; Guan SY; Yao JH; Li W; Ye WC; Zhang DM*; Zhang CX*.Novel cytotoxic nine-membered macrocyclic polysulfur cembranoid lactones from the soft coral Sinularia sp.Tetrahedron, 2014, 70(38): 6851-58.
81 Luo SL; Huang XJ; Wang Y; Jiang RW; Wang L; Bai LL; Peng QL; Song CL; Zhang DM*; Ye WC*.Isocoumarins from American cockroach (Periplaneta americana) and their cytotoxic activities.Fitoterapia, 2014, 95: 115-20.
82 Deng LJ#; Hu LP#; Peng QL; Yang XL; Bai LL; Yiu A; Li Y; Tian HY; Ye WC*; Zhang DM*.Hellebrigenin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt.Chemico-Biological Interactions, 2014, 219: 184-94.
83 Wang J#; Zhang DM#; Jia JF; Peng QL; Tian HY; Wang L*; Ye WC*.Cyclodepsipeptides from the ascocarps and insect-body portions of fungus Cordyceps cicadae.Fitoterapia, 2014, 97: 23-7.
84 Liu DL#; Li YJ#; Yao N; Xu J; Chen ZS; Yiu A; Zhang CX; Ye WC*; Zhang DM*.Acerinol, cyclolanstane triterpenoid from Cimicifuga acerina, reverses ABCB1-mediated multidrug resistance in HepG2/ADM and MCF-7/ADR cells.European Journal of Pharmacology, 2014, 733: 34-44.
85 Xiang QF#; Zhang DM#; Wang JN; Zhang HW; Zheng ZY; Yu DC; Li YJ; Xu J; Chen YJ; Shang CZ*.Cabozantinib reverses multidrug resistance of human hepatoma HepG2/adr cells by modulating the function of P-glycoprotein.Liver International, 2014, 35(3): 1010-1023.
86 孙一蕊; 范春林; 王贵阳; 王英; 张冬梅; 周杰; 邓海鸣; 叶文才.消渴丸HPLC特征图谱研究.药物分析杂志, 2014, (03): 539-546.
87 Zheng J#; Deng LJ#; Chen MF; Xiao XZ; Xiao SW; Guo CP; Xiao GK; Bai LL; Ye WC; Zhang DM*; Chen HR*.Elaboration of thorough simplified vinca alkaloids as antimitotic agents based on pharmacophore similarity.European Journal of Medicinal Chemistry, 2013, 65: 158-167.
88 Wang Y#; Wang WJ#; Su C; Zhang DM; Xu LP; He RR; Wang L; Zhang J; Zhang XQ*; Ye WC*.Cytotoxic quassinoids from Ailanthus altissima.Bioorganic & Medicinal Chemistry Letters, 2013, 23(3): 654-7.
89 Liu ZW#; Yang TT#; Wang WJ*; Li GQ; Tang BQ; Zhang QW*; Fan CL; Zhang DM; Zhang XQ*; Ye WC.Ervahainine A,a new cyano-substituted oxindole alkaloid from Ervatamia hainanensis.Tetrahedron Letters, 2013, 54(48): 6498-500.
90 Chen JJ; Patel A; Sodani K; Xiao ZJ; Tiwari AK; Zhang DM; Li YJ; Yang DH; Ye WC; Chen SD*; Chen ZS*.BBA,a synthetic derivative of 23-hydroxybutulinic acid, reverses multidrug resistance by inhibiting the efflux activity of MRP7 (ABCC10).PloS One, 2013, 8(9).
91 Li GL#; Han WL#*; Jiang W; Zhang DM; Ye WC; Chen XJ; MA AD*.Quantitative determination of arenobufagin in rat plasma by ultra fast liquid chromatography–tandem mass spectrometry and its application in a pharmacokinetic study.Journal of Chromatography B, 2013, 939: 86-91.
92 Zhang CX#*; Zhang DM#; Chen MF; Guan SY; Yao JH; He XX; Lei LF; Zhong Y; Wang ZF; Ye WC*.Antiproliferative triterpenoid saponins from the stem of Psychotria sp.Planta Medica, 2013, 79(11): 798-86.
93 Zhang Dongmei#; Liu JS#; Deng LJ; Chen MF; Yiu A; Cao HH; Tian HY; Fung KP; Kurihara H; Pan JX*; Ye WC*.Arenobufagin, a natural bufadienolide from toad venom, induced apoptosisand autophagy in human hepatocellular carcinoma cells though inhibition ofPI3K/Akt/mTOR pathway.Carcinogenesis, 2013, 34(6): 1331-42.
94 Zhang DM#; Li YJ#; Shu C; Yao N; Chen WM; Chen ZS*; Ye WC*.Bipiperidinyl derivatives of 23-hydroxybetulinic acid reverse theresistance of HepG2/ADM and MCF-7/ADR cells.Anti-cancer Drugs, 2013, 24(5): 441-54.
95 Wang WJ; Wang L*; Huang X.J; Jiang RW; Yang XL; Zhang DM; Chen WM; Tang BQ; Wang Y; Zhang XQ*; Ye WC*.Two pairs of new benzofuran enantiomers with unusual skeletons from Eupatorium chinense.Tetrahedron Letters, 2013, 54(26): 3321-3324.
96 周杰#; 孙一蕊#; 邓海鸣; 张冬梅; 范春林; 叶文才*.消渴丸化学成分的研究.中成药, 2013, 35(10): 2205-9.
97 Liu ZW#; Yang TT#; Wang WJ*; Li G.Q; Tang BQ; Zhang, QW*; Fan CL; Zhang DM; Zhang XQ*; Ye WC.Ervahainine A, a new cyano-substituted oxindole alkaloid from Ervatamia hainanensis.Tetrahedron Letters, 2013, 54(48): 6498-6500.
98 Chen JJ; Patel A; Sodani K; Xiao ZJ; Tiwari AK; Zhang DM; Li YJ; Yang DH; Ye WC; Chen SD*; Chen ZS*.BBA, a Synthetic Derivative of 23-hydroxybutulinic Acid, Reverses Multidrug Resistance by Inhibiting the Efflux Activity of MRP7 (ABCC10).PLoS One, 2013, 8(9).
99 Tian HY; Luo SL; Liu JS; Wang L; Wang Y; Zhang DM; Zhang XQ; Jiang RW*; Ye WC*.C23 Steroids from the Venom of Bufo bufo gargarizans.Journal of Natural Products, 2013, 76(10): 1842-1847.
100 Li GL#; Han WL#*; Jiang W; Zhang DM; Ye WC; Chen XJ; MA AD*.Quantitative determination of arenobufagin in rat plasma by ultra fastliquid chromatography–tandem mass spectrometry and itsapplication in a pharmacokinetic study.Journal of Chromatography B, 2013, 939(卷): 86-91.
101 Zhang CX#*; Zhang DM#; Chen MF; Guan SY; Yao JH; He XX; Lei LF; Zhong Y; Wang ZF; Ye WC*.Antiproliferative triterpenoid saponins from the stem of Psychotria sp..Planta Medica, 2013, 79(11): 978-986.
102 Zhang DM#; Li YJ#; Shu C; Yao N; Chen WM; Chen ZS*; Ye WC*.Bipiperidinyl derivatives of 23-hydroxybetulinic acid reverse the resistance of HepG2/ADM and MCF-7/ADR cells.Anti-Cancer Drugs, 2013, 24(5): 441-454.
103 Zheng J#; Deng LJ#; Chen MF; Xiao XZ; Xiao SW; Guo CP; Xiao GK; Bai LL; Ye WC; Zhang DM*; Chen HR*.Elaboration of thorough simplified vinca alkaloids as anti-mitotic agents based on pharmacophore similarity.European Journal of Medicinal Chemistry, 2013, 65(卷): 158-167.
104 Shi JM#; Bai LL#; Zhang DM*; Yiu, A; Yin ZQ; Han WL; Liu JS; Li Y; Fu DY; Ye WC*.Saxifragifolin D induces the interplay between apoptosis and autophagy in breast cancer cells through ROS-dependent endoplasmic reticulum stress.Biochemical Pharmacology, 2013, 85(7): 913-926.
105 Liu JS#; Zhang DM#; Li Y; Chen WM; Ruan ZX; Deng LJ; Wang LW; Tian HY; Yiu A; Fan CL; Luo HB; Liu SW; Wang Y; Xiao GK; Chen LX*; Ye WC*.Discovery of bufadienolides as a novel class of ClC-3 chloride channel activators with antitumor activities.Journal of Medicinal Chemistry, 2013, 56(14): 5734-5743.
106 Zhang DM#; Liu JS#; Deng LJ; Chen MF; Yiu A; Cao HH; Tian HY; Fung KP; Kurihara H; Pan JX*; Ye WC*.Arenobufagin, a natural bufadienolide from toad venom, induced apoptosis and autophagy in human hepatocellular carcinoma cells though inhibition of PI3K/Akt/mTOR pathway.Carcinogenesis, 2013, 34(6): 1331-1342.
107 Zhang Dongmei#; Shu Chang#; Chen Junjiang#; Sodani Kamlesh; Wang Jiao; Bhatnagar Jaya; Lan Ping; Ruan Zhixiong; Xiao Zhijie; Ambudkar Suresh V.; Chen Weimin; Chen Zhesheng*; Ye Wencai*.BBA, a derivative of 23-hydroxybetulinic acid, potently reverses ABCB1-mediated drug resistance in vitro and in vivo.Molecular Pharmaceutics, 2012, 9(11): 3147-3159.
108 Shao M; Wang Y*; Jian YQ; Huang XJ; Zhang DM; Tang QF; Jiang RW; Sun XG; Lv ZP; Zhang XQ*; Ye WC*.Guadial A and Psiguadials C and D, three unusual meroterpenoids from Psidium guajava.Organic Letters, 2012, 14(20): 5262-5265.
109 Zhang Dong-mei#; Li Yong#; Cheang Wai-san#; Lau Chi-wai; Lin Shun-ming; Zhang Qian-lan; Yao Nan; Wang Ying; Wu Xin; Huang Yu*; Ye Wen-cai*.Cajaninstilbene Acid relaxes rat renal arteries: roles of ca(2+) antagonism and protein kinase C-dependent mechanism.PLoS One, 2012, 7(10): 1-7.
110 Zhang, Dong Mei; Liu, Jun Shan; Tang, Ming Kuen; Yiu, Anita; Cao, Hui hui; Jiang, Lei; Chan, Judy Yuet Wa; Tian, Hai Yan; Fung, Kwok Pui; Ye, Wen Cai*.Bufotalin from Venenum Bufonis inhibits growth of multidrug resistant HepG2 cells through G(2)/M cell cycle arrest and apoptosis.European Journal of Pharmacology, 2012, 692(1-3): 19-28.
111 Wang CQ; Wang L*; Fan CL; Zhang DM; Huang XJ; Jiang RW; Bai LL; Shi JM; Wang Y*; Ye WC*.Ilelic Acids A and B, two unusual triterpenes with a seven-membered ring from Ilex latifolia.Organic Letters, 2012, 14(16): 4102-4105.
112 Zhao BX; Wang Y*; Zhang DM; Huang XJ; Bai LL; Yan Y; Chen JM; Lu TB; Wang YT; Zhang QW*; Ye WC*.Virosaines A and B, two new birdcage-shaped securinega alkaloids with an unprecedented skeleton from Flueggea virosa.Organic Letters, 2012, 14(12): 3096-3099.
113 Li MM#; Wu S#; Liu Z; Zhang W; Xu J; Wang Y; Liu JS; Zhang DM; Tian HY; Li YL*; Ye WC*.Arenobufagin, a bufadienolide compound from toad venom, inhibits VEGF-mediated angiogenesis through suppression of VEGFR-2 signaling pathway.Biochemical Pharmacology, 2012, 83(9): 1251-60.
114 高明雅; 沈伟哉*; 吴颜晖; 曹长姝; 张冬梅; 高江晖.钩吻生物碱单体对肝癌细胞体外抑制作用机制的初步研究.中药材, 2012, 35(3): 438-442.
115 Kumar P; Zhang DM; Degenhardt K*; Chen ZS*.Autophagy and transporter-based multi-drug resistance.Cells, 2012, 1(3): 558-75.
116 Li Y; Zhang DM; Xu J; Shi JM; Jiang L; Yao N; Ye WC*.Discovery and development of natural heat shock protein 90 inhibitors incancer treatment.Acta Pharmaceutica Sinica B, 2012, 2(3): 238-45.
117 石俊敏; 张冬梅*; 姚楠; 冯国培; 王英; 栗原博; 叶文才.三萜皂苷Saxifragifolin D抑制人肝癌耐药细胞 HepG2/ADM生长并诱导调亡作用研究.中国药理学通报, 2012, 28(1): 34-8.
118 李勇; 邓丽娟; 武小林; 杨小林; 叶文才; 张冬梅*.文多灵对大鼠肾血管的舒张作用.中国药理学通报, 2012, 28(8): 1096-1100.
119 Wang CH#; Wang GC#; Wang Y; Zhang XQ; Huang XJ; Zhang DM; Chen MF; Ye WC*.Cytotoxic dimeric indole alkaloids from Catharanthus roseus.Fitoterapia, 2012, 83(4): 765-769.
120 Zhang XQ#*; Xu FF#; Wang L; Huang MY; Liu Z; Zhang DM; Wang GC; Li YL; Ye WC*.Two pairs of new diastereoisomeric flavonolignans from the seeds of Hovenia acerba.Phytochemistry Letters, 2012, 5(2): 292-295.
121 Shao M; Wang Y*; Jian YQ; Huang XJ; Zhang DM; Tang QF; Jiang RW; Sun XG; Lv ZP; Zhang XQ*; Ye WC*.Guadial A and psiguadials C and D, three unusual meroterpenoids from Psidium guajava.Organic Letters, 2012, 14(20): 5262-5265.
122 Wang CQ; Wang L*; Fan CL; Zhang DM; Huang XJ; Jiang RW; Bai LL; Shi JM; Wang Y*; Ye WC*.Ilelic acids A and B, two unusual triterpenes with a seven-membered ring from Ilex latifolia.Organic Letters, 2012, 14(16): 4102-4105.
123 Zhao BX; Wang Y*; Zhang DM; Huang XJ; Bai LL; Yan Y; Chen JM; Lu TB; Wang YT; Zhang QW*; Ye WC*.Virosaines A and B, two new birdcage-shaped Securinega alkaloids with an unprecedented skeleton from Flueggea virosa.Organic Letters, 2012, 14(12): 3096-3099.
124 Zhang DM#; Li Y#; Cheang WS#; Lau CW; Lin SM; Zhang QL; Yao N; Wang Y; Huang Y*; Ye WC*.Cajaninstilbene Acid relaxes rat renal arteries: roles of Ca2+ antagonism and protein kinase C-dependent mechanism.PLoS One, 2012, 7(卷).
125 Zhang DM#; Shu C#; Chen JJ#; Sodani K; Wang J; Bhatnagar J; Lan P; Ruan ZX; Xiao ZJ; Ambudkar SV; Chen WM; Chen ZS*; Ye WC*.BBA, a derivative of 23-hydroxybetulinic acid, potently reverses ABCB1-mediated drug resistance in vitro and in vivo.Molecular Pharmaceutics, 2012, 9(11): 3147-3159.
126 石俊敏; 张冬梅; 姚楠; 冯国培; 王英; 栗原博; 叶文才.三萜皂苷Saxifragifolin D抑制人肝癌耐药细胞HepG2/ADM生长并诱导细胞凋亡作用研究.Chinese Pharmacological Bulletin, 2012, (01): 34-38.
127 Wang GC; Zhong XZ; Zhang DM; Wang Y; Zhang XQ; Jiang RW; Li YL; Wang J; Yao XS; Ye WC*.Two pairs of epimeric indole alkaloids from Catharanthus roseus.Planta Medica, 2011, 77(15): 1739-41.
128 李朋军; 沈伟哉; 叶文才; 张冬梅; 孙艳*.点地梅提取物saxifragifolin B体外抗实体瘤活性研究.中国病理生理杂志, 2011, 27(5): 838-842.
129 刘俊姗; 张冬梅; 陈敏锋; 李满妹; 罗青岛; 栗原博; 叶文才*.沙蟾毒精抑制血管生成的作用.药学学报, 2011, 46(5): 527-533.
130 罗海兵; 李华荣; 刘善文; 彭爽; 刘振锋; 叶文才; 张冬梅; 陈丽新*; 王立伟*.蟾蜍灵激活低分化鼻咽癌细胞氯通道.中国病理生理杂志, 2011, 27(4): 672-676.
131 Wang L; Yin ZQ*; Zhang QW; Zhang XQ; Zhang DM; Liu K; Li YL; Yao XS; Ye WC*.Five new C-21 steroidal glycosides from Periploca sepium.Steroids, 2011, 76(3): 238-243.
132 曹惠慧; 张冬梅; 刘俊姗; 侯春英; 栗原博; 叶文才*.沙蟾毒精抑制肝癌HepG2细胞黏附、迁移和侵袭的作用.中国药理学通报, 2011, 27(1): 19-23.
133 Zhang XQ; Ip FC; Zhang DM; Chen LX; Zhang W; Li YL; Ip NY; Ye WC*.Triterpenoids with neurotrophic activity from Ganoderma lucidum.Natural Product Research, 2011, 25(17): 1607-13.
134 柏志全#; 李春英#; 李媛; 马文波; 朱林燕; 叶文才; 张冬梅; 王立伟*; 陈丽新*.氯通道在华蟾酥毒基诱导的鼻咽癌细胞凋亡中起重要作用.中国病理生理杂志, 2011, 27(5): 833-837.
135 罗海兵; 李华荣; 刘善文; 彭爽; 刘振锋; 叶文才; 张冬梅; 陈丽新*; 王立伟*.蟾蜍灵激活低分化鼻咽癌细胞氯通道.中国病理生理杂志, 2011, 27(4): 672-676.
136 李朋军; 沈伟哉; 叶文才; 张冬梅; 孙艳*.点地梅提取物saxifragifolin B体外抗实体瘤活性研究.中国病理生理杂志, 2011, 27(5): 838-842.
137 舒畅; 刘俊珊; 张冬梅; 李振清; 卢艳仪; 朱文婷; 叶文才*.观辣树药理作用研究进展.国际药学研究杂志, 2011, 38(4): 270-274.
138 曹惠慧; 张冬梅; 刘俊珊; 候春英; 栗原博; 叶文才*.沙蟾毒精抑制肝癌HepG2细胞粘附、迁移和侵袭作用研究.中国药理学通报, 2011, 27(1): 19-23.
139 刘俊珊; 张冬梅; 陈敏峰; 李满妹; 罗青岛; 栗原博; 叶文才*.沙蟾毒精抑制血管新生的作用.药学学报, 2011, 46(5): 527-533.
140 Wang L; Yin ZQ*; Zhang QW; Zhang XQ; Zhang DM; Liu K; Li YL; Yao XS; Ye WC*.Five new C21 steroidal glycosides from Periploca sepium.Steroids, 2011, 76(3): 238-243.
141 Lan P#; Wang J#; Zhang DM; Shu C; Cao HH; Sun PH; Wu XM; Ye WC*; Chen WM*.Synthesis and antiproliferative evaluation of 23-hydroxybetulinic acid derivatives.European Journal of Medicinal Chemistry, 2011, 46(6): 2490-2502.
142 Zhao BX; Wang Y*; Zhang DM; Jiang RW; Wang GC; Shi JM; Huang XJ; Chen WM; Che CT; Ye WC*.Flueggines A and B, two new dimeric indolizidine alkaloids from Flueggea virosa.Organic Letters, 2011, 13(15): 3888-3891.
143 Wang GC; Zhong XZ; Zhang DM; Wang Y; Zhang XQ; Jiang RW; Li YL; Yao XS; Ye WC*.Two Pairs of Epimeric Indole Alkaloids from Catharanthus roseus.Planta Medica, 2011, 77(15): 1739-1741.
144 Tian HY; Wang L; Zhang XQ; Zhang DM; Wang Y; Liu JS; Jiang RW; Ye WC*.New bufadienolides and C-23 steroids from the venom of Bufo bufo gargarizans.Steroids, 2010, 75(12): 884-890.
145 Chen, Jian-Xin; Huang, Shen-Hui; Wang, Lei; Han, Wei-Li; Wang, Ying; Zhang, Dong-Mei; Ye, Wen-Cai*.Two Pairs of Enantiomeric Neolignans from Lobelia chinensis.Natural Product Communications, 2010, 5(10): 1627-1630.
146 吴霞; 李药兰*; 张冬梅; 叶文才.25种中草药体外抑制鼻咽癌细胞增殖活性研究.中成药, 2010, 32(12): 1339-45.
147 蓝平; 张冬梅; 陈卫民*; 叶文才*.白桦酸类化合物的结构修饰与生物活性研究进展.药学学报, 2010, 45(11): 1339-45.
148 Tian HY; Wang L; Zhang XQ; Wang Y; Zhang DM; Jiang RW; Liu Z; Liu JS; Li YL; Ye WC*.Bufogargarizins A and B: two novel 19-norbufadienolides with unprecedented skeletons from the venom of Bufo bufo gargarizans.Chemistry-A European Journal, 2010, 16(36): 10989-10993.
149 Tian HY; Wang L; Zhang XQ; Zhang DM; Wang Y; Liu JS; Jiang RW; Ye WC*.New bufadienolides and C(23) steroids from the venom of Bufo bufo gargarizans.Steroids, 2010, 75(12): 884-890.
150 Shao M#; Wang Y#; Liu Z; Zhang DM; Cao HH; Jiang RW; Fan CL; Zhang XQ; Chen HR; Yao XS; Ye WC*.Psiguadials A and B, two novel meroterpenoids with unusual skeletons from the leaves of Psidium guajava.Organic Letters, 2010, 12(21): 5040-5043.
151 Zhang DM#; Lin SM#; Lau CW; Yiu A; Wang J; Li Y; Fan CL; Huang Y*; Ye WC*.Amenoside A3-induced relaxation in rat renal arteries: roles of endothelium and Ca2+ channel inhibition.Planta Medica, 2010, 76(16): 1814-1819.
152 Wang GC; Wang Y; Williams ID; Sung HHY; Zhang XQ; Zhang DM; Jiang RW; Yao XS; Ye WC*.Andrographolactone, an unique diterpene from Andrographis paniculata.Tetrahedron Letters, 2009, 50(34): 4824-6.
153 Jiang RW*; Wang Y; Gao H; Zhang DM; Ye WC.Molecular structures and π–π interactions of quercitrin and morusin hydroperoxide.Journal of Molecular Structure, 2009, 920(1-3): 383-386.
154 刘俊珊; 张冬梅; 栗原博; 叶文才*. 蟾酥及其活性成分抗肿瘤作用研究进展.国际药学研究杂志, 2009, 36(2): 115-20.
155 Tang PMK; Liu XZ; Zhang DM; Fong WP; Fung KP*.Pheophorbide a based phytodynamic therapy induces apoptosis via mitochondril-mediated pathway in human uterine carcinosarcoma.Cancer Biology & Therapy, 2009, 8(6): 533-9.
156 Tang PMK; Zhang DM; Xuan NHB; Tsui SKW; Waye MMY; Kong SK; Fong WP; Fung KP*.Photodynamic therapy inhibits P-glycoprotein mediated multidrug resistance via JNK activation in human hepatocellular carcinoma using the photosensitizer pheophorbide a.Molecular Cancer, 2009, 8: 56.
157 Wang Y; Zhang DM; Ye WC*; Yin ZQ; Fung KP; Zhao SX; Yao XS.Triterpenoid saponins from Androsace umbellata and their anti-proliferative activities in human hepatoma cells.Planta Medica, 2008, 74(10): 1280-1284.
158 Zhang DM; Wang Y; Tang MK; Chan YW; Lam HM; Ye WC; Fung KP*.Saxifragifolin B from Androsace umhellata induced apoptosis on human hepatoma cells.Biochemical and Biophysical Research Communications, 2007, 362(3): 759-765.
T159 ang MK; Zhang DM; Chan JY; Lee KM; Kong SK; Tsui SK; Waye MM; Mak TC; Fung KP*.Apoptotic effect of stearic acid, an active compound isolated from Oldenlandia diffusa, on human hepatoma cells.Research Journal of Medical Sciences, 2007, 1(1): 30-8.
160 Tang MK; Chan JY; Zhang DM; AU WN; Kong SK; Tsui SK; Waye MM; Mak TC; Fung KP*.Pheophorbide a, an active component in Scutellaria barbata,reverses P-glycoprotein-mediated multidrug resistance on human hepatoma cellline R-HepG2.Cancer Biology & Therapy, 2007, 6: 504-9.
161 Zhang DM; Tang PK; Chan JY; Lam HM; Au SW; Kong SK; Tsui SK; Waye MM; TC Mak TC; Fung KP*.Anti-proliferative effect of ursolic acid on multidrug resistant hepatoma cells via induction of apoptosis.Cancer Biology & Therapy, 2007, 6(9): 1381-1389.
162 殷志琦; 王英; 张冬梅; 叶文才; 赵守训*.金丝桃属植物化学成分研究进展.中国野生植物资源, 2004, 23(1): 6-11.
163 张冬梅; 胡立宏; 叶文才*; 赵守训. 白蜡树的化学成分研究.中国天然药物, 2003, 1(2): 79-81.
164 Mai, Weiqian; Chen, Minfeng; Huang, Maohua; Zhong, Jincheng; Chen, Jian; Liu, Xiaoyong; Deng, Juan; Yang, Xiaoxi; Ye, Wencai; Zhang, Rijia*; Zhou, Qing*; Zhang, Dongmei*.Targeting platelet-derived growth factor receptor beta inhibits the proliferation and motility of human pterygial fibroblasts.Expert Opinion on Therapeutic Targets.
165 Ang S#; Liu XM#; Huang XJ; Zhang DM; Zhang W; Wang L*; Ye WC*.Four new amaryllidaceae alkaloids from lycoris radiata and their cytotoxicity.Planta Medica, 81(18): 1712-8.
166 张冬梅*.Saxifragifolin D induces the interplay between apoptosis and autophagy in breast cancer cells through ROS-dependent endoplasmic reticulum stress.Biochemical Pharmacology.
会议论文：
1 Yao, Nan; Sun, Haiyan; Huang, Maohua; Ye, Wencai; Chen, SiBao; Zhang, Dong-Mei.The cycloartane triterpenoid ADCX impairs autophagic degradation through Akt overactivation and promotes apoptotic cell death in multidrug-resistant HepG2/ADM cells.Annual Meeting of the American-Association-for-Cancer-Research (AACR), 2019-03-29 To 2019-04-03.
2 张冬梅; 陈丽新; 叶文才; 邓丽娟; 刘俊珊; 胡丽萍; 彭群龙; 田海研; 韩伟立; 李媛; 曹惠慧.蟾毒内酯化合物抗肿瘤活性评价及其作用机制研究.中国药理学会第十三次全国学术大会, 2015-11-02.
3 张冬梅.Molecular Mechanisms for Anti-Cancer Activities of Bufadienolides.上海中医药与天然药物国际大会分会场学术报告, China,Shanghai, 2015-10-21.
4 李英杰; 刘道路; 张冬梅; 叶文才.菠萝蜜烷型三萜化合物升麻醇逆转肿瘤多药耐药作用及机制研究.中国化学会.
5 殷志琦; 王磊; 李承花; 张冬梅; 王英; 赵明; 车镇涛; 叶文才。点地梅中活性三萜皂苷的研究.中国化学会.
6 叶文才; 张冬梅; 陈立新; 刘俊珊; 田海妍.基于蟾毒内酯类化合物研究肿瘤细胞凋亡和自噬的作用机制.2013年全国药物化学学术会议暨第四届中英药物化学学术会议, 中国,山东省, 2013-11-01.
7 叶文才; 张冬梅; 陈立新; 陈卫民; 刘俊珊; 田海妍; 李满妹.蟾毒内酯类化合物诱导肿瘤细胞自噬和凋亡的分子机制研究.第八届全国化学生物学学术会议, 中国,上海市, 2013-09-15.
8 郑晶; 肖绪枝; 张冬梅; 陈河如; 叶文才.乙烯桥连的二吲哚类化合物的设计合成.中国化学会、国家自然科学基金委员会, 中国,海南省,海口市, 2012-11-08.
9 刘俊珊; 张冬梅; 田海妍; 叶文才.沙蟾毒精靶向PI3K/Akt/mTOR调控肝癌细胞自噬和凋亡的相互作用.中国化学会第28届学术年会, 中国,四川省, 2012-04-13.
10 张冬梅*; 舒畅; 王娇; 蓝平; 陈卫民; 叶文才.23-羟基白桦酸衍生物耐药逆转P-糖蛋白介导的肿瘤多药耐药.中国化学会第28届学术年会, 中国,四川省, 2012-04-13.
11 肖绪枝; 郑晶; 陈敏峰; 张冬梅; 陈河如; 叶文才.长春质碱的自身偶合以及抗肿瘤作用研究.2011年全国药物化学学术会议——药物的源头创新, 中国,广东省, 2011-11-17.
12 Liu JS; Zhang Dongmei; Chen MF; Tian HY; Ye WC.Critical role of PI3K/Akt/mTOR signalingpathway in arenobufagin-induced autophagy and apoptosis in hepatocellular carcinoma.第七届化学生物学会议论文集, China,Jiangsu,Nanjing, 2011-08.
13 Shu C; Zhang Dongmei; Wang J; Lan P; Chen WM; Ye WC.Specific reversal of P-glycoprotein-mediated multidrug resistance by a novel potent modulator, 23-hydroxybutulinic acid derivatives BBA.第七届化学生物学会议论文集, China,Jiangsu,Nanjing, 2011-08.
14 郑晶; 肖绪枝; 陈敏峰; 张冬梅; 陈河如; 叶文才.取代苯乙烯基吲哚类化合物的设计合成及抗肿瘤作用研究.中国药学会.
15 叶文才; 王英; 张晓琦; 张冬梅; 王国才; 王磊; 车镇涛; 姚新生.几种重要中药及天然药物化学成分的再研究.中国化学会第八届天然有机化学学术研讨会, 2010-10-08.
16 叶文才; 王英; 张晓琦; 张冬梅; 王国才; 王磊; 车镇涛; 姚新生.几种重要中药及天然药物化学成分的再研究(摘要).全国第9届天然药物资源学术研讨会, 2010-07-18.
17 Zhang Dongmei.Novel triterpenoid saponins from Androsace umbellate induced apoptosis in human hepatomacells.98th Annual Meeting of the American-Association-for-Cancer Research, China,Hebei,Langfang, 2007-04-14 to 2007-04-18.
所获荣誉：
1. 国家万人计划青年拔尖人才。
2. 教育部新世纪优秀人才。
3. 广东省青年珠江学者。
4. 广东省自然科学基金杰出青年科学基金获得者。
5. 2017年，广东省丁颖科技奖 科技人物奖。
6. 2022年，广东省三八红旗手 标兵。
所获奖励：
1.2018年，中药和天然药物的三萜及其皂苷成分研究与应用，叶文才; 王广基; 吴晓明; 范春林; 王英; 张晓琦; 张冬梅; 汪豪; 刘东来; 裴红，中华人民共和国国务院, 科技进步, 国家二等奖。
2.2021年，岭南常用中草药活性成分发现和质控体系构建的关键技术与应用,张冬梅,广东省人民政府, 科技进步, 省部一等奖, 2021.
3.2017年，中药和天然药物的三萜及其皂苷成分研究与应用，叶文才; 张冬梅; 王英; 张晓琦; 范春林; 汪豪; 殷志琦; 张庆文; 王磊; 李满妹; 刘东来; 裴红; 李药兰; 王国才; 黄晓君广东省人民政府, 科技进步, 省部一等奖, 2017.
4.2014年，中药白头翁活性成分的系统研究与应用，张冬梅（4/15），广东省科技厅, 广东省科学技术进步奖, 一等奖, 2014.
5.2013年，入选领跑者5000--中国精品科技期刊顶尖学术论文奖，张冬梅，中国科学技术信息研究所, 其它, 其它, 2013.
6.《中国药理学通报》创刊三十周年优秀审稿专家，张冬梅，中国药理学会, 其它, 其它, 2013.
7.《药学学报》第六届优秀论文奖，张冬梅，药学学报编辑部, 其它, 其它, 2012.
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